| The Legend of Zelda | Shigeru Miyamoto, Takashi Tezuka, Nintendo | 50 | action role-playing game, action-adventure game, fantasy video game, Japanese role-playing video game |
| Fire Emblem | Intelligent Systems | 23 | tactical role-playing game |
| Mario | Shigeru Miyamoto, Nintendo | 16 | educational video game, adventure video game, puzzle video game, role-playing video game, party video game, platform game, racing video game, sports video game |
| WarioWare | Intelligent Systems, Nintendo Software Planning & Development, Nintendo Research & Development 1 | 14 | — |
| Wars | Hudson Soft, Intelligent Systems, Nintendo Research & Development 1, WayForward Technologies, Kuju Ltd. | 14 | turn-based strategy video game |
| Professor Layton | Akihiro Hino, Level-5 | 13 | adventure video game, puzzle video game |
| Rayman | Michel Ancel, Ubisoft Paris, Ubisoft Romania, Q2083518, Ubisoft Milan, Ubisoft Sofia, Ubisoft Casablanca, Ubisoft Shanghai | 13 | adventure video game, action game, platform game |
| Wii | Bandai Namco Studios, Nintendo Entertainment Analysis & Development, Nintendo Software Planning & Development, Ganbarion, Nintendo Entertainment Planning & Development, skip Ltd., Vanpool, Good-Feel, Nintendo Cube, Prope, Arzest, Chunsoft +1 | 12 | simulation video game, party video game |
| Star Fox | Q-Games, Q1576758, Nintendo Entertainment Analysis & Development, Nintendo Entertainment Planning & Development, Argonaut Games, Namco, Rare Ltd. | 9 | shoot 'em up, action-adventure game |
| Fatal Frame | Keisuke Kikuchi, Makoto Shibata, Grasshopper Manufacture, Koei Tecmo Holdings, Nintendo Software Planning & Development | 7 | survival horror |
| Pokémon Mystery Dungeon | Spike Chunsoft, Chunsoft | 7 | roguelike |
| Bit Generations | skip Ltd. | 5 | action game, puzzle video game |
| Final Fantasy Crystal Chronicles | Square Enix | 5 | action role-playing game, role-playing game, city-building game |
| Rhythm Heaven | J.P ROOM Inc, Q122741, Nintendo Software Planning & Development, TNX | 5 | rhythm game |
| Mario Artist | Nintendo Entertainment Analysis & Development | 4 | — |
| Osu! Tatakae! Ouendan | iNiS | 3 | rhythm game |
| Pokémon Ranger | HAL Laboratory, Creatures | 3 | action role-playing game |
| Pokémon Stadium | HAL Laboratory | 3 | strategy video game |
| Kid Icarus | — | 2 | platform game |
| LCD games from The Legend of Zelda series | Epoch Co., Nintendo Research & Development 1 | 2 | action-adventure game, fighting game |
| Xeno | Monolith Soft Inc. | 2 | action role-playing game, role-playing video game |
| 3D Classics | Arika | 1 | — |
| Nintendo World Championships | — | 1 | — |
| Batman: Arkham Trilogy | Rocksteady Studios | — | action game |