| I Got Games | — | — | — |
| Iam8bit | Los Angeles | 2005 | entertainment |
| IBA Group | Prague | 2005 | software industry |
| Iber Software | — | — | video game industry |
| IBM | Armonk | June 16, 1911 | software industry |
| Ice-Pick Lodge | Moscow | 2002 | video game industry |
| Iceflake Studios | Tampere | 2007 | video game industry |
| Icetesy SPRL | — | — | video game industry |
| Idea Factory | Shibuya | October 27, 1994 | video game industry |
| Idea Factory International | Gardena | September 30, 2013 | video game industry |
| Ideaworks Game Studio | Bayswater | 1997 | — |
| Idigicon Limited | — | 1980 | — |
| Ignition Banbury | — | — | — |
| Iko | Paris | November 24, 2009 | — |
| IllFonic | Denver | 2007 | video game industry |
| Illusion Labs | Malmö | 2007 | video game industry |
| Illuvium Labs | — | — | video game industry |
| Illwinter Game Design | Lund | September 27, 2001 | video game industry |
| ILMxLAB | — | 2015 | — |
| Image Space Incorporated | Ann Arbor | 1992 | video game industry |
| Imageepoch | Tokyo | June 9, 2005 | video game industry |
| Imagic | Los Gatos | 1981 | video game industry |
| Imagination Games | Adelaide | 1984 | game |
| ImaginEngine | Venice | 1994 | video game industry |
| Imangi Studios | Raleigh | 2008 | video game industry |
| Incentive Software | Reading | 1983 | — |
| Incinerator Studios | Carlsbad | 2005 | video game industry |
| Incognito Entertainment | Salt Lake City | May 1999 | video game industry |
| Incredible Technologies | Arlington Heights | 1985 | video game industry |
| Increpare games | — | — | — |
| Index+ | — | — | video game developer |
| Indie Built | Salt Lake City | 1983 | video game industry |
| IndieRevo | — | — | — |
| Infinite Dreams | Gliwice | 2006 | video game industry |
| Infinite Dreams Software | — | — | — |
| Infinite State Games | Tonbridge | July 17, 2013 | — |
| Infinity Plus Two | St Kilda | 1989 | video game industry |
| Infinity Ward | Woodland Hills | 2002 | video game industry |
| Infocom | Cambridge | June 22, 1979 | video game industry |
| Ini3 Digital | Bangkok | 2004 | entertainment |
| Ink Stains Games | — | — | — |
| Inkle | Cambridge | November 2011 | — |
| Inland Productions | Carol Stream | — | video game industry |
| InLogic Software | Banská Bystrica | 2005 | video game industry |
| Innovative Minds | — | — | — |
| Institute of National Remembrance | — | 1998 | — |
| Intelligent Games | London | 1988 | video game industry |
| Intelligent Systems | Kyoto | December 1986 | video game industry |
| Intense Limited | Tokyo | July 2002 | video game industry |
| Interactive Data Visualization Inc. | Lexington | 2000 | — |
| Interactive Magic | — | 1994 | video game industry |
| Interactive Technology | — | — | — |
| Interchannel | Shinjuku | 1987 | video game industry |
| Intergalactic Development | Davenport | — | video game industry |
| International Fencing Federation | Switzerland | November 29, 1913 | — |
| International Games System | New Taipei City | October 1991 | video game industry |
| Inti Creates | Ichikawa | May 8, 1996 | video game industry |
| IntraCorp | Miami | 1984 | video game industry |
| Introversion Software | Walton-on-Thames | 2001 | — |
| Invictus Games | Debrecen | 2000 | video game industry |
| Invincibles Studio | — | 2004 | — |
| Iron Galaxy Studios | Chicago | 2008 | video game industry |
| Iron Gate Studio | — | April 2019 | video game industry |
| Ironhide Game Studio | Montevideo | January 26, 2010 | video game industry |
| Ironwood Studios | — | — | — |
| ISCO | — | 1987 | video game industry |
| Ishtar Games | Tourcoing | August 2005 | video game industry |
| Isto Inc. | Calgary | January 19, 2018 | video game industry |
| It Matters Games | Berlin | — | video game industry |