| Company | Based in | Founded | Industry |
|---|---|---|---|
| Z-Software | Dortmund | 2008 | video game industry |
| Zachtronics | Redmond | 2011 | video game industry |
| Zemina | South Korea | 1981 | video game industry |
| ZeniMax Media | Rockville | May 26, 1999 | video game industry |
| Zenobi | — | 1982 | — |
| ZeptoLab | London | 2010 | — |
| Zipper Interactive | Redmond | 1995 | video game industry |
| Zippo Games | — | — | — |
| Zombie Studios | New-York Tribune | 1994 | video game industry |
| Zone | — | 1997 | — |
| Zono | Costa Mesa | 1991 | video game industry |
| Zoom Out Games | — | 2011 | video game industry |
| Zoo Publishing | Cincinnati | 2001 | — |
| Zoë Mode | Brighton | 2007 | — |
| Zuxxez Entertainment | Karlsruhe | 1994 | video game industry |
| ZyX | — | — | video game industry |