| R-Next | — | — | video game industry |
| Rabbit Software | — | 1982 | — |
| Rabén & Sjögren | Stockholm | 1942 | — |
| RAC7 Games | Vancouver | 2014 | video game developer |
| Racjin | Yodogawa-ku | April 17, 1995 | video game industry |
| Radarsoft | Alphen aan den Rijn | 1984 | video game industry |
| Radiangames | — | March 2010 | video game industry |
| Radical Forge | Middlesbrough | October 13, 2016 | — |
| Rage Games | Liverpool | 1992 | — |
| Rainbow Arts | Düsseldorf, Gütersloh | 1984 | video game industry |
| Raiser Games | Madrid | — | — |
| RandomSpin Games | — | — | video game industry |
| Rapid Snail | — | 2015 | video game industry |
| RapidEyeMovers | London | June 16, 2021 | — |
| Rare Ltd. | Twycross | 1985 | — |
| Rarebyte | — | 2006 | video game industry |
| Rat Cliff Games | Lanzarote | — | video game industry |
| Ratalaika Games | León | May 14, 2013 | video game industry |
| Raven Software | Middleton, Madison | 1990 | video game industry |
| Ravenscourt | — | — | video game industry |
| Ravn Studio | Drammen | April 10, 2002 | video game industry |
| Raw Fury | Stockholm | 2015 | video game industry |
| Raw Thrills | Skokie | 2001 | video game industry |
| Rayark Inc. | Taipei | September 2011 | video game development |
| Raylight Games | Benevento | 2000 | video game industry |
| Razorback Developments | Lewes | 2003 | — |
| Razorworks | — | 1996 | — |
| RDI Video Systems | — | 1982 | video game industry |
| Ready at Dawn | Irvine | 2003 | video game industry |
| Reakktor Media | Hanover | 1991 | — |
| Reality Labs | Irvine, Menlo Park, California | 2020 | software industry |
| Realmforge Studios | Munich | 2008 | video game industry |
| Realtime Associates | El Segundo | 1986 | video game industry |
| Realtime Games Software | — | — | — |
| Recloak | — | — | — |
| Red Art Games | Champs-sur-Marne | December 18, 2017 | wholesale (business-to-business) of computers, computer peripheral equipment and software |
| Red Barrels | Montreal | 2011 | video game industry |
| Red Candle Games | Zhongzheng District | September 2015 | video game industry |
| Red Dot Games | — | — | — |
| Red Entertainment | Tokyo | 1976 | video game industry |
| Red Games Co. | Santa Monica | 2018 | video game industry |
| Red Hook Studios | Vancouver | 2013 | video game industry |
| Red Limb Studio | — | 2016 | video game industry |
| Red Orb Entertainment | Novato | 1997 | video game industry |
| Red Phantom Games | — | — | — |
| Red Redemption | Oxford | — | — |
| Redblack Spade | — | — | video game industry |
| RedDeerGames | Warsaw | — | video game industry |
| Reef Entertainment | — | April 15, 2005 | — |
| Reflex Interactive | Manchester | 2022 | — |
| Regular Studio | — | — | video game industry |
| Rekka Games | Gond-Pontouvre | November 15, 2022 | video game industry |
| Rekoo | Beijing | August 21, 2007 | video game industry |
| Relentless Software | Brighton | 2003 | — |
| Reliance Games | Mumbai | 2006 | video game industry |
| Render Cube | — | — | video game industry |
| Renegade Kid | Austin | 2007 | video game industry |
| Renegade Software | — | 1990 | video game industry |
| Repixel8 | — | — | — |
| Replay Studios | Hamburg | 2002 | video game industry |
| Reply Game Studios | Milan | — | video game industry |
| Resnijars | — | — | video game industry |
| Resolution Games | Stockholm | 2015 | video game industry |
| Retrific | Hamm | March 2013 | — |
| Retro Army Limited | Leith | July 2011 | — |
| Retrotainment Games | Pittsburgh | — | video game industry |
| Reverb Publishing | — | — | video game industry |
| Revolt Games | Lyon | April 19, 2019 | video game publishing |
| Rhythm and Hues Studios | El Segundo | 1987 | visual effects |
| Ricochet | — | — | — |
| Rino Marketing Ltd. | — | — | — |
| Riot Forge | — | — | video game industry |
| Riot Games | West Los Angeles, Los Angeles, California | 2006 | video game industry |
| Rising Moon Games | — | — | video game industry |
| Rising Star Games | Hitchin | 2004 | — |
| Roberts Space Industries International, Ltd. | Manchester | February 7, 2014 | — |
| Robot Entertainment | Plano | 2009 | video game industry |
| Robot Invader | Menlo Park | 2011 | video game industry |
| Robot Teddy | — | 2019 | — |
| RobTop Games | Stockholm | March 8, 2012 | — |
| Robust Games | — | March 23, 2021 | — |
| Rocket Adrift | — | — | video game industry |
| Rocketcat Games | — | — | video game industry |
| Rockhead Studios | Porto Alegre | 2011 | video game industry |
| Rockpool Games | — | — | — |
| Rockstar Leeds | Leeds | 1997 | — |
| Rockstar London | London | 2005 | — |
| Rockstar Vancouver | Vancouver | 1998 | video game industry |
| Rogue Games | Los Angeles | 2018 | video game industry |
| Rogue Sun | — | — | — |
| Roomah Games | — | 2020 | video game industry |
| Roost Games | Diemen | — | video game industry |
| Rootless Studio | — | — | video game industry |
| Royal Industries | — | 1964 | — |
| Ruby Party | — | 1990 | video game industry |
| RumbleSushi | Norwich | 2010 | — |
| Rundisc | Fenouillet | October 9, 2018 | video game industry |
| Runecraft | Dewsbury | 1997 | — |
| Runic Games | Seattle | 2008 | video game industry |
| Runner Duck | Brighton | 2017 | — |
| Running with Scissors | Tucson | 1996 | video game industry |
| Ryu ga Gotoku Studio | Ota | August 31, 2011 | video game industry |