| I am a Teacher: Teami no Kiso | educational video game | Royal Industries | Famicom Disk System |
| I AM BUTTER VR | casual game, adventure video game, role-playing video game | — | Microsoft Windows |
| I Can't Escape: Darkness | adventure video game | — | Microsoft Windows, macOS, Linux |
| I commissioned some bees | hidden object game | Follow The Fun | Microsoft Windows |
| I commissioned some bees 12 Days | casual game | Follow The Fun | Microsoft Windows |
| I commissioned some bees 15 | casual game | — | Microsoft Windows |
| I commissioned some bees 3 | hidden object game | Follow The Fun | Microsoft Windows |
| I commissioned some bees 4 | hidden object game | Follow The Fun | Microsoft Windows |
| I commissioned some bees 6 | hidden object game | Follow The Fun | Microsoft Windows |
| I dream of you and ice cream | adventure video game | — | Microsoft Windows |
| I Love Finding Birds | casual game | — | Microsoft Windows, macOS |
| I Love Finding Critters | casual game | — | Microsoft Windows, macOS |
| I Love Finding MORE Cats | casual game | — | Microsoft Windows, macOS |
| I Love Traffic | — | — | web browser |
| I wanna fly | — | — | — |
| I Woke Up Next to You Again. | visual novel | Angela He | Microsoft Windows, macOS, Linux, web browser |
| I'm a King | simulation video game, adventure video game, strategy video game, role-playing video game | — | Microsoft Windows |
| I'm on Observation Duty 6 | — | — | Microsoft Windows, macOS, Linux |
| I, Cyborg | — | Choice of Games | Microsoft Windows, macOS, Linux |
| I-War | — | Imagitec Design | Atari Jaguar |
| Iblard: Laputa no Kaeru Machi | adventure video game | System Sacom | — |
| IBomber Attack | — | Cobra Mobile | Microsoft Windows, macOS, Linux |
| ICBM | — | — | Microsoft Windows |
| ICE FLAME | casual game, adventure video game, action game, action-adventure game | — | Microsoft Windows |
| Icewind Dale: Enhanced Edition | role-playing video game | Beamdog | Microsoft Windows, macOS, Linux, Android |
| Icicle Works | — | — | Commodore 16, ZX Spectrum, Commodore Plus/4, Commodore 64 |
| Icosi-do | casual game, strategy video game | — | Microsoft Windows |
| Idle Campaign | casual game, simulation video game, adventure video game, strategy video game, role-playing video game | — | Microsoft Windows |
| Idle Evolution | casual game, simulation video game, strategy video game | — | Microsoft Windows, macOS, Linux |
| Idle Roboto | casual game, strategy video game | — | Microsoft Windows |
| Idle Sand Castle | casual game | — | Microsoft Windows |
| Idle Skilling | casual game, simulation video game | — | Microsoft Windows |
| Idle Theme Park Tycoon | — | — | Android |
| Iesabel | action game, role-playing video game | — | Microsoft Windows, macOS, Linux |
| Ignis Avis Venatio | visual novel | — | Microsoft Windows, macOS, Linux |
| Ignition | — | Unique Development Studios | Microsoft Windows, macOS, DOS, Linux |
| Igor: The Game | — | Santa Cruz Games | Microsoft Windows, Wii |
| IGP Manager | — | iGP Games | web browser, Android |
| IHRA Drag Racing 2004 | racing video game | — | — |
| Ikai | horror video game | — | Microsoft Windows, Xbox Series X and Series S |
| Ikari III: The Rescue | action game | SNK, SNK | Nintendo Entertainment System, Commodore 64 |
| IKARIE XB 1 aneb Návrat na Zemi | interactive fiction | — | ZX Spectrum |
| Ikinari Happy Bell | eroge, visual novel | Terios | Microsoft Windows |
| IKO 39 | adventure video game, action game, action-adventure game | — | Microsoft Windows |
| Ikusa Megami 2 ~Ushinawareshi Kioku e no Chinkonka~ | eroge, visual novel | Eushully | Microsoft Windows |
| Ikusa Otome Valkyrie "Anata ni Subete o Sasagemasu" | eroge, visual novel | — | Microsoft Windows |
| Ikusa Otome Valkyrie 2 "Shu yo, Midara na Watashi o Oyurushi Kudasai..." | eroge, visual novel | — | Microsoft Windows |
| Ikusa Otome Valkyrie 3 "Anata no Yō na Otoko ni wa Zettai ni Kusshimasen......!" | eroge, visual novel | — | Microsoft Windows |
| Illumizzle: Finding the lost light | casual game, adventure video game | — | Microsoft Windows |
| Illusion of L'Phalcia | Japanese role-playing video game | Exe-Create | Microsoft Windows |
| Illustrated | jigsaw puzzle video game | BorderLeap | macOS |
| Illuvium: Arena | strategy video game, auto battler | Illuvium Labs | Microsoft Windows |
| Illuvium: Overworld | monster-taming game, massively multiplayer online role-playing game, adventure video game | Illuvium Labs | Microsoft Windows |
| Image Fight II: Operation Deepstriker | vertically scrolling shooter | — | Wii U |
| Imagine Fashion Party | — | Lexis Numérique | Wii |
| Imagine Interior Designer | simulation video game | Anuman | Nintendo DS |
| Imagine Teacher | simulation video game | — | Nintendo DS |
| Imagine: Animal Doctor | — | Q188273 | Nintendo DS |
| Imagine: Makeup Artist | — | Global A Entertainment | Nintendo DS |
| Imitating Zombies | — | — | Microsoft Windows |
| Imouto o Kegashita Kioku | eroge, visual novel, video game with LGBT character | Hamham-soft | Microsoft Windows, Android |
| Imperialism II: Age of Exploration | turn-based strategy video game | Frog City Software | Classic Mac OS, Microsoft Windows |
| Imperium | — | Electronic Arts | DOS, Atari ST |
| Imperium Romanum | — | — | DOS |
| Impious Pumpkins | casual game, strategy video game | — | Microsoft Windows |
| Impostor Inside Us | casual game, action game | — | Microsoft Windows |
| Imōto Smile | eroge, visual novel | — | Microsoft Windows |
| In a search of a new home | casual game, simulation video game, adventure video game, action game, action-adventure game, strategy video game, role-playing video game, racing video game, sports video game | — | Microsoft Windows |
| In Extremis | action game | — | Microsoft Windows |
| In Extremis DX | — | — | Xbox Series X and Series S |
| In Other Waters | adventure video game | Jump Over the Age | Microsoft Windows, macOS |
| In Shape | adventure video game | QuickBobber | Microsoft Windows |
| In Sky Girls | visual novel | Pearflower | Microsoft Windows |
| In Sound Mind | horror video game | Q54149333 | Microsoft Windows, Xbox Series X and Series S |
| IN THE BUILDING: CATS 3 | casual game | — | Microsoft Windows |
| In The Shadows | puzzle video game, platform game | — | Microsoft Windows, macOS, Linux |
| Inaccessible world | simulation video game, adventure video game | — | Microsoft Windows |
| Inagawa Junji: Kyoufu no Yashiki | visual novel | — | — |
| Inagawa Junji: Mayonaka no Taxi | visual novel | — | — |
| Inca Blocks | — | — | Microsoft Windows, macOS, Linux |
| Incident Commander | simulation video game, strategy video game | BreakAway Games | Microsoft Windows, macOS |
| Incidente em Varginha | first-person shooter | — | Microsoft Windows |
| Incoming | — | Rage Games | Microsoft Windows, arcade video game machine |
| Incoming Forces | — | Rage Games | Microsoft Windows |
| Inconsistencies | adventure video game | — | Microsoft Windows |
| Incredible Dracula 3: Family Secret | casual game, adventure video game | New Bridge Games | Microsoft Windows, macOS |
| Incredible Dracula: Chasing Love | casual game, adventure video game, strategy video game | New Bridge Games | Microsoft Windows, macOS |
| Indiana Jones a Chrám zkázy | adventure video game | — | ZX Spectrum |
| Indiana Jones and the Last Crusade | — | Taito | Nintendo Entertainment System |
| Indiana Jones and the Last Crusade: The Action Game | — | Tiertex Design Studios | DOS, Nintendo Entertainment System, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| Industry Giant | business simulation game | JoWooD Ebensee | Microsoft Windows |
| IndyCar Series 2005 | — | — | Microsoft Windows |
| Inertial Drift | — | — | Microsoft Windows |
| Infected Shelter | adventure video game, action game, action-adventure game, role-playing video game | — | Microsoft Windows |
| Infection Rate | — | — | Microsoft Windows |
| Infectonator: Survivors | simulation video game, adventure video game, action game, action-adventure game, strategy video game, role-playing video game | Toge Productions | Microsoft Windows, macOS |
| Inferno | adventure video game, role-playing video game | Aldorlea Games | Microsoft Windows |
| Inferno Pool | — | Dark Energy Digital | PlayStation 3 |
| Infestor | — | — | — |
| Infiniball | casual game, action game | — | Microsoft Windows |
| Infinite Tao | casual game, action game | — | Microsoft Windows |
| Infinite Turtles | puzzle video game | — | Microsoft Windows, macOS, Linux |
| INFINITY CHALLENGE | — | — | Microsoft Windows, macOS |
| Infinity Escape | — | — | Microsoft Windows, macOS, Linux |
| Inflatable doll | casual game | — | Microsoft Windows |
| Inglorious Pirate | adventure video game, action game, action-adventure game | — | Microsoft Windows |
| Ingrid's Back | — | Level 9 Computing | DOS, ZX Spectrum, Amstrad CPC, Amstrad PCW, MSX |
| INHUMAN | adventure video game, action game, action-adventure game | — | Microsoft Windows |
| Initial D Second Stage: Taipingu Kantō Saisoku Purojekuto | — | — | — |
| Initial D: Street Stage | racing video game | — | PlayStation Portable |
| Injustice 2 Mobile | — | — | — |
| Inline | casual game, strategy video game | — | Microsoft Windows, macOS, Linux |
| Innocent Until Caught | — | Divide By Zero | DOS |
| Innocent VR | — | — | Microsoft Windows |
| Ino | — | — | Microsoft Windows |
| Insane Insects: The Inception | — | — | Microsoft Windows |
| Inside a Star-filled Sky | shooter game | Jason Rohrer | Microsoft Windows, macOS, Linux |
| Inside the Box | casual game | — | Microsoft Windows |
| Insincere | action game | Astronomic Games | Microsoft Windows |
| INSOMNIA: The Ark | action game, role-playing video game | — | Microsoft Windows |
| Inspector Gadget: Mad Robots Invasion | action game | — | — |
| Instant Sports Paradise | — | BreakFirst | Xbox Series X and Series S |
| Insurgence - Second Assault | — | — | Microsoft Windows |
| Insurgency | first-person shooter | New World Interactive | Microsoft Windows, macOS, Linux |
| Intelligence: Cats | — | Laush Studio | Microsoft Windows |
| Intelligence: Dogs | casual game | Laush Studio | Microsoft Windows |
| Intelligent Qube | puzzle video game | Sony Interactive Entertainment | — |
| Intensive Exposure | simulation video game, action game | Fireline Games | Microsoft Windows |
| Interference: Dead Air | simulation video game, adventure video game | — | Microsoft Windows |
| Intergalactic Rescue | action game | — | Microsoft Windows, macOS, Linux |
| Intergalactic Taxi Co. | casual game | — | Microsoft Windows |
| Interlude | visual novel | — | Microsoft Windows |
| International Cricket Captain 2006: Ashes Edition | — | Empire Interactive | personal computer |
| International Cricket Captain III | — | Empire Interactive | Microsoft Windows |
| International Cue Club | — | Takara | Microsoft Windows |
| International Space Station Tour VR | casual game | The House of Fables | Microsoft Windows |
| International Superstar Soccer 3 | association football video game | Konami | Microsoft Windows, Nintendo GameCube |
| International Superstar Soccer 64 | association football video game | Konami | Nintendo 64 |
| International Superstar Soccer Pro | association football video game | Konami | — |
| Internet Cafe Simulator | simulation video game, adventure video game | — | Microsoft Windows |
| Internet Court | casual game, simulation video game | Oh, a Rock! Studios | Microsoft Windows, macOS, Linux |
| Interphase | — | The Assembly Line | Microsoft Windows, DOS, Linux |
| Interrogation: You will be deceived | visual novel | — | Microsoft Windows, macOS, Linux |
| Interstate '82 | vehicular combat game | — | Microsoft Windows |
| Intimate Relationship | casual game, simulation video game, action game, role-playing video game | William at Oxford | Microsoft Windows |
| Into the Radius VR | action game | — | Microsoft Windows |
| Intruder on the Bridge | adventure video game, role-playing video game | — | Microsoft Windows |
| Inua – A Story in Ice and Time | point-and-click adventure | The Pixel Hunt, Iko, Arte France | Microsoft Windows, macOS |
| Inukami! feat. Animation | visual novel | ASCII Media Works | Nintendo DS |
| Invade-a-Load | — | — | Commodore 64 |
| Invasion 2: Doomed | casual game, adventure video game | Itera Laboratories | Microsoft Windows |
| Invasion Deutschland | first-person shooter, action game | Davilex Games | Microsoft Windows |
| Invasion Zero | action game, massively multiplayer online game | — | Microsoft Windows, macOS, Linux |
| INVITATION To FEAR | action game | — | Microsoft Windows |
| Ionia | casual game, adventure video game | Rotu Entertainment | Microsoft Windows |
| Irides: Master of Blocks | puzzle video game | — | — |
| Iriya no Sora, UFO no Natsu II | sound novel | — | Nintendo DS |
| Iron Aces | — | — | — |
| Iron Commando | — | Arcade Zone | Super Nintendo Entertainment System |
| Iron Disco | — | — | Microsoft Windows |
| Iron Feather | action role-playing game | Konami | Nintendo DS |
| Iron Fisticle | — | — | Microsoft Windows |
| Iron Front: Liberation 1944 | — | — | Microsoft Windows |
| IRON GUARD | action game, strategy video game | — | Microsoft Windows |
| Iron Reckoning | adventure video game, action game, action-adventure game, role-playing video game | — | Microsoft Windows, macOS, Linux |
| Ironclads 2: War of the Pacific | — | — | Microsoft Windows |
| Ironclads: Schleswig War 1864 | — | — | Microsoft Windows |
| Irritability & Mood Swings | — | — | Microsoft Windows |
| Is Simon There? | casual game, adventure video game | — | Microsoft Windows |
| Isbarah | — | — | Microsoft Windows, macOS, Linux |
| Isekai ni Tensei Shitara Densetsu no Yūsha (Uke) Deshita!? | — | — | Microsoft Windows |
| Ishar 2: Messengers of Doom | role-playing video game | Silmarils | DOS, Atari ST |
| Ishar: Legend of the Fortress | role-playing video game | Silmarils | Classic Mac OS, DOS, Atari ST |
| Island Diary | — | — | Microsoft Windows |
| Island Invasion | — | — | Microsoft Windows, macOS, Linux |
| Island Xtreme Stunts | — | — | — |
| Island Xtreme Stunts | — | Silicon Dreams Studios | Microsoft Windows |
| Islanders: New Shores | — | Coatsink | Microsoft Windows, Xbox Series X and Series S |
| Isle Escape: The House | escape room video game | — | Android |
| Isle of Arrows | strategy video game | — | Microsoft Windows, macOS |
| Isoland | — | Cotton Game | Microsoft Windows, macOS, Android |
| ISOLAND3: Dust of the Universe | casual game, adventure video game, strategy video game | Cotton Game | Microsoft Windows, macOS |
| Isolomus | casual game, adventure video game | Michael Rfdshir | Microsoft Windows, Linux |
| Isotiles 2 | casual game, strategy video game | — | Microsoft Windows, macOS |
| It gets so lonely here | adventure video game, visual novel | — | Microsoft Windows, macOS, Linux, Android |
| IT TAKES THE BALL | casual game | — | Microsoft Windows |
| It's Killing Time | adventure video game, role-playing video game | Choice of Games | Microsoft Windows, macOS, Linux |
| It's Spring Again | casual game | — | Microsoft Windows, macOS, Linux |
| Itadaki Street 2: Neon Sign wa Bara Iro ni | — | ASCII Corporation | Super Nintendo Entertainment System |
| Itadaki Street DS | puzzle video game | Armor Project | Nintendo DS |
| Item Collector - Pirates | casual game, simulation video game, adventure video game, strategy video game, role-playing video game | Boogygames Studios | Microsoft Windows |
| IWO: Bloodbath in the Bonins | — | — | Microsoft Windows, macOS |
| Izeriya | 2D platform game, adventure video game | — | Microsoft Windows |
| Izumo | bishōjo game, role-playing video game | Studio e.go! | Microsoft Windows |
| Izumo 2 ~Gakuen Kyousoukyoku~ | — | Studio e.go! | Microsoft Windows |
| Izumo Zero | strategy video game | Studio e.go! | Microsoft Windows |